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5AM Ventures

5AM Ventures is a leading investment firm focused on funding and building next-generation life sciences companies

4:59 INITIATIVE

4:59 is 5AM’s hands-on internal effort to discover, incubate, and fund breakthrough science. We seek to partner alongside academics and entrepreneurs – often serving as an extension of the operating team – to establish proof-of-concept data that will enable a Series A Financing.

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VENTURE CAPITAL

5AM Ventures Strategy primarily invests in private therapeutic companies. The funds are typically early-stage focused, with an emphasis on Series A companies.

PUBLIC EQUITY

5AM Opportunities Strategy invests in small and mid-cap public and later-stage private biotech and life science companies.

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Supporting companies that are working to solve important healthcare needs via cutting-edge breakthroughs in medicine and science

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Pushing the healthcare industry forward

  • Under Management
    $ 0 B
    Capital Raised Since Inception
    Data as of January 1, 2025

    We’re a life science venture capital firm founded in 2002 and currently investing $450M from 5AM Ventures VII and $300M from 5AM Opportunities II.

  • Under Management
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    PORTFOLIO COMPANIES

    Our focus is biopharmaceuticals, drug delivery technologies and life science instruments.

  • Under Management
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    ONGOING CLINICAL TRIALS

    Historically, our portfolio companies have over 90,000 patients enrolled across 450+ test sites in clinical trials.

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